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Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats

BACKGROUND: The amygdala-kindled rat is a model for human temporal lobe epilepsy and activity-dependent synaptic plasticity. Hippocampal RNA isolated from amygdala-kindled rats at different kindling stages was analyzed to identify kindling-induced genes. Furthermore, effects of the anti-epileptic dr...

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Detalles Bibliográficos
Autores principales: Christensen, Kenneth V, Leffers, Henrik, Watson, William P, Sánchez, Connie, Kallunki, Pekka, Egebjerg, Jan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848232/
https://www.ncbi.nlm.nih.gov/pubmed/20105316
http://dx.doi.org/10.1186/1471-2202-11-9