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Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

Although genome-wide association studies (GWAS) of complex traits have yielded more reproducible associations than had been discovered using any other approach, the loci characterized to date do not account for much of the heritability to such traits and, in general, have not led to improved underst...

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Detalles Bibliográficos
Autores principales: Nicolae, Dan L., Gamazon, Eric, Zhang, Wei, Duan, Shiwei, Dolan, M. Eileen, Cox, Nancy J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848547/
https://www.ncbi.nlm.nih.gov/pubmed/20369019
http://dx.doi.org/10.1371/journal.pgen.1000888