Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations

The recent success of genome-wide association studies (GWAS) is now followed by the challenge to determine how the reported susceptibility variants mediate complex traits and diseases. Expression quantitative trait loci (eQTLs) have been implicated in disease associations through overlaps between eQ...

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Detalles Bibliográficos
Autores principales: Nica, Alexandra C., Montgomery, Stephen B., Dimas, Antigone S., Stranger, Barbara E., Beazley, Claude, Barroso, Inês, Dermitzakis, Emmanouil T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848550/
https://www.ncbi.nlm.nih.gov/pubmed/20369022
http://dx.doi.org/10.1371/journal.pgen.1000895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848550/
https://www.ncbi.nlm.nih.gov/pubmed/20369022
http://dx.doi.org/10.1371/journal.pgen.1000895

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