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Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations
The recent success of genome-wide association studies (GWAS) is now followed by the challenge to determine how the reported susceptibility variants mediate complex traits and diseases. Expression quantitative trait loci (eQTLs) have been implicated in disease associations through overlaps between eQ...
Autores principales: | Nica, Alexandra C., Montgomery, Stephen B., Dimas, Antigone S., Stranger, Barbara E., Beazley, Claude, Barroso, Inês, Dermitzakis, Emmanouil T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848550/ https://www.ncbi.nlm.nih.gov/pubmed/20369022 http://dx.doi.org/10.1371/journal.pgen.1000895 |
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