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The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

Antibody protection against flaviviruses is associated with the development of neutralizing antibodies against the viral envelope (E) protein. Prior studies with West Nile virus (WNV) identified therapeutic mouse and human monoclonal antibodies (MAbs) that recognized epitopes on domain III (DIII) of...

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Detalles Bibliográficos
Autores principales: Shrestha, Bimmi, Brien, James D., Sukupolvi-Petty, Soila, Austin, S. Kyle, Edeling, Melissa A., Kim, Taekyung, O'Brien, Katie M., Nelson, Christopher A., Johnson, Syd, Fremont, Daved H., Diamond, Michael S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848552/
https://www.ncbi.nlm.nih.gov/pubmed/20369024
http://dx.doi.org/10.1371/journal.ppat.1000823