Cargando…
The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1
Antibody protection against flaviviruses is associated with the development of neutralizing antibodies against the viral envelope (E) protein. Prior studies with West Nile virus (WNV) identified therapeutic mouse and human monoclonal antibodies (MAbs) that recognized epitopes on domain III (DIII) of...
Autores principales: | Shrestha, Bimmi, Brien, James D., Sukupolvi-Petty, Soila, Austin, S. Kyle, Edeling, Melissa A., Kim, Taekyung, O'Brien, Katie M., Nelson, Christopher A., Johnson, Syd, Fremont, Daved H., Diamond, Michael S. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848552/ https://www.ncbi.nlm.nih.gov/pubmed/20369024 http://dx.doi.org/10.1371/journal.ppat.1000823 |
Ejemplares similares
-
Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope
por: Austin, S. Kyle, et al.
Publicado: (2012) -
Potent Dengue Virus Neutralization by a Therapeutic Antibody with Low Monovalent Affinity Requires Bivalent Engagement
por: Edeling, Melissa A., et al.
Publicado: (2014) -
Therapeutic Efficacy of Antibodies Lacking FcγR against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies
por: Williams, Katherine L., et al.
Publicado: (2013) -
Correction: Therapeutic Efficacy of Antibodies Lacking Fc. Receptor Binding against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies
por: Williams, Katherine L., et al.
Publicado: (2013) -
Structural basis of West Nile virus neutralization by a therapeutic antibody
por: Nybakken, Grant E., et al.
Publicado: (2005)