Cryptococcus neoformans Overcomes Stress of Azole Drugs by Formation of Disomy in Specific Multiple Chromosomes

Cryptococcus neoformans is a haploid environmental organism and the major cause of fungal meningoencephalitis in AIDS patients. Fluconazole (FLC), a triazole, is widely used for the maintenance therapy of cryptococcosis. Heteroresistance to FLC, an adaptive mode of azole resistance, was associated w...

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Detalles Bibliográficos
Autores principales: Sionov, Edward, Lee, Hyeseung, Chang, Yun C., Kwon-Chung, Kyung J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848560/
https://www.ncbi.nlm.nih.gov/pubmed/20368972
http://dx.doi.org/10.1371/journal.ppat.1000848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848560/
https://www.ncbi.nlm.nih.gov/pubmed/20368972
http://dx.doi.org/10.1371/journal.ppat.1000848

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