Disheveled Hair and Ear (Dhe), a Spontaneous Mouse Lmna Mutation Modeling Human Laminopathies

BACKGROUND: Investigations of naturally-occurring mutations in animal models provide important insights and valuable disease models. Lamins A and C, along with lamin B, are type V intermediate filament proteins which constitute the proteinaceous boundary of the nucleus. LMNA mutations in humans caus...

Descripción completa

Detalles Bibliográficos
Autores principales: Odgren, Paul R., Pratt, Craig H., MacKay, Carole A., Mason-Savas, April, Curtain, Michelle, Shopland, Lindsay, Ichicki, Tsutomu, Sundberg, John P., Donahue, Leah Rae
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848607/
https://www.ncbi.nlm.nih.gov/pubmed/20376364
http://dx.doi.org/10.1371/journal.pone.0009959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848607/
https://www.ncbi.nlm.nih.gov/pubmed/20376364
http://dx.doi.org/10.1371/journal.pone.0009959

Ejemplares similares