The Combinatorial PP1-Binding Consensus Motif (R/K)x( (0,1))V/IxFxx(R/K)x(R/K) Is a New Apoptotic Signature

BACKGROUND: Previous studies established that PP1 is a target for Bcl-2 proteins and an important regulator of apoptosis. The two distinct functional PP1 consensus docking motifs, R/Kx((0,1))V/IxF and FxxR/KxR/K, involved in PP1 binding and cell death were previously characterized in the BH1 and BH3...

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Detalles Bibliográficos
Autores principales: Godet, Angélique N., Guergnon, Julien, Maire, Virginie, Croset, Amélie, Garcia, Alphonse
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848619/
https://www.ncbi.nlm.nih.gov/pubmed/20376316
http://dx.doi.org/10.1371/journal.pone.0009981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848619/
https://www.ncbi.nlm.nih.gov/pubmed/20376316
http://dx.doi.org/10.1371/journal.pone.0009981

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