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The Combinatorial PP1-Binding Consensus Motif (R/K)x( (0,1))V/IxFxx(R/K)x(R/K) Is a New Apoptotic Signature
BACKGROUND: Previous studies established that PP1 is a target for Bcl-2 proteins and an important regulator of apoptosis. The two distinct functional PP1 consensus docking motifs, R/Kx((0,1))V/IxF and FxxR/KxR/K, involved in PP1 binding and cell death were previously characterized in the BH1 and BH3...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848619/ https://www.ncbi.nlm.nih.gov/pubmed/20376316 http://dx.doi.org/10.1371/journal.pone.0009981 |