An Implantable Vascularized Protein Gel Construct That Supports Human Fetal Hepatoblast Survival and Infection by Hepatitis C Virus in Mice

BACKGROUND: Widely accessible small animal models suitable for the study of hepatitis C virus (HCV) in vivo are lacking, primarily because rodent hepatocytes cannot be productively infected and because human hepatocytes are not easily engrafted in immunodeficient mice. METHODOLOGY/PRINCIPAL FINDINGS...

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Detalles Bibliográficos
Autores principales: Harding, Martha J., Lepus, Christin M., Gibson, Thomas F., Shepherd, Benjamin R., Gerber, Scott A., Graham, Morven, Paturzo, Frank X., Rahner, Christoph, Madri, Joseph A., Bothwell, Alfred L. M., Lindenbach, Brett D., Pober, Jordan S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848675/
https://www.ncbi.nlm.nih.gov/pubmed/20376322
http://dx.doi.org/10.1371/journal.pone.0009987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848675/
https://www.ncbi.nlm.nih.gov/pubmed/20376322
http://dx.doi.org/10.1371/journal.pone.0009987

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