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BCL2 inhibits Cell Adhesion, Spreading, and Motility by Enhancing Actin Polymerization

BCL2 is best known as a multifunctional anti-apoptotic protein. However, little is known about its role in cell adhesive and motility events. Here, we show that BCL2 may play a role in the regulation of cell adhesion, spreading, and motility. When BCL2 was overexpressed in cultured murine and human...

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Detalles Bibliográficos
Autores principales: Ke, Hengning, Parron, Vandy I., Reece, Jeff, Zhang, Jennifer Y., Akiyama, Steven K., French, John E.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848692/
https://www.ncbi.nlm.nih.gov/pubmed/20142842
http://dx.doi.org/10.1038/cr.2010.21