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p53 Suppresses Structural Chromosome Instability Following Mitotic Arrest In Human Cells

The p53 tumor suppressor inhibits the proliferation of cells which undergo prolonged activation of the mitotic checkpoint. However, the function of this antiproliferative response is not well defined. Here we report that p53 suppresses structural chromosome instability following mitotic arrest in hu...

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Detalles Bibliográficos
Autores principales: Dalton, W. Brian, Yu, Bing, Yang, Vincent W.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848712/
https://www.ncbi.nlm.nih.gov/pubmed/20062083
http://dx.doi.org/10.1038/onc.2009.477