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p53 Suppresses Structural Chromosome Instability Following Mitotic Arrest In Human Cells
The p53 tumor suppressor inhibits the proliferation of cells which undergo prolonged activation of the mitotic checkpoint. However, the function of this antiproliferative response is not well defined. Here we report that p53 suppresses structural chromosome instability following mitotic arrest in hu...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848712/ https://www.ncbi.nlm.nih.gov/pubmed/20062083 http://dx.doi.org/10.1038/onc.2009.477 |