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Roles of Coactivators in Hypoxic Induction of the Erythropoietin Gene
BACKGROUND: Hypoxia-inducible expression of the erythropoietin (EPO) gene is mediated principally by hypoxia-inducible factor 2α (HIF-2α) in Hep3B cells under physiologic conditions. How/whether p300/CBP and the members of p160 coactivator family potentiate hypoxic induction of endogenous EPO and ot...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848849/ https://www.ncbi.nlm.nih.gov/pubmed/20368990 http://dx.doi.org/10.1371/journal.pone.0010002 |