A Forward Chemical Screen in Zebrafish Identifies a Retinoic Acid Derivative with Receptor Specificity

BACKGROUND: Retinoids regulate key developmental pathways throughout life, and have potential uses for differentiation therapy. It should be possible to identify novel retinoids by coupling new chemical reactions with screens using the zebrafish embryonic model. PRINCIPAL FINDINGS: We synthesized no...

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Detalles Bibliográficos
Autores principales: Das, Bhaskar C., McCartin, Kellie, Liu, Ting-Chun, Peterson, Randall T., Evans, Todd
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848850/
https://www.ncbi.nlm.nih.gov/pubmed/20368991
http://dx.doi.org/10.1371/journal.pone.0010004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848850/
https://www.ncbi.nlm.nih.gov/pubmed/20368991
http://dx.doi.org/10.1371/journal.pone.0010004

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