Dynamic Dependence on ATR and ATM for Double-Strand Break Repair in Human Embryonic Stem Cells and Neural Descendants

The DNA double-strand break (DSB) is the most toxic form of DNA damage. Studies aimed at characterizing DNA repair during development suggest that homologous recombination repair (HRR) is more critical in pluripotent cells compared to differentiated somatic cells in which nonhomologous end joining (...

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Detalles Bibliográficos
Autores principales: Adams, Bret R., Golding, Sarah E., Rao, Raj R., Valerie, Kristoffer
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848855/
https://www.ncbi.nlm.nih.gov/pubmed/20368801
http://dx.doi.org/10.1371/journal.pone.0010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848855/
https://www.ncbi.nlm.nih.gov/pubmed/20368801
http://dx.doi.org/10.1371/journal.pone.0010001

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