Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

BACKGROUND: Chemotherapy-induced reduction in tumor load is a function of apoptotic cell death, orchestrated by intracellular caspases. However, the effectiveness of these therapies is compromised by mutations affecting specific genes, controlling and/or regulating apoptotic signaling. Therefore, it...

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Detalles Bibliográficos
Autores principales: Wong, Chew Hooi, Iskandar, Kartini Bte, Yadav, Sanjiv Kumar, Hirpara, Jayshree L., Loh, Thomas, Pervaiz, Shazib
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848860/
https://www.ncbi.nlm.nih.gov/pubmed/20368806
http://dx.doi.org/10.1371/journal.pone.0009996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848860/
https://www.ncbi.nlm.nih.gov/pubmed/20368806
http://dx.doi.org/10.1371/journal.pone.0009996

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