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A Dedicated Promoter Drives Constitutive Expression of the Cell-Autonomous Immune Resistance GTPase, Irga6 (IIGP1) in Mouse Liver

BACKGROUND: In general, immune effector molecules are induced by infection. METHODOLOGY AND PRINCIPAL FINDINGS: However, strong constitutive expression of the cell-autonomous resistance GTPase, Irga6 (IIGP1), was found in mouse liver, contrasting with previous evidence that expression of this protei...

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Detalles Bibliográficos
Autores principales: Zeng, Jia, Parvanova, Iana Angelova, Howard, Jonathan C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848866/
https://www.ncbi.nlm.nih.gov/pubmed/20368812
http://dx.doi.org/10.1371/journal.pone.0006787