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Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders

PURPOSE: While chronic glucocorticoid (GC) therapy leads to ocular hypertension in about one third of individuals, almost all primary open-angle glaucoma (POAG) patients show this response and are called “steroid responders.” Two differentially spliced isoforms of the glucocorticoid receptor (GR), G...

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Detalles Bibliográficos
Autores principales: Fingert, John H., Alward, Wallace L., Wang, Kai, Yorio, Thomas, Clark, Abbot F.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848919/
https://www.ncbi.nlm.nih.gov/pubmed/20376328