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Combinatorial interaction between two human serotonin transporter gene variable number tandem repeats and their regulation by CTCF

Two distinct variable number tandem repeats (VNTRs) within the human serotonin transporter gene (SLC6A4) have been implicated as predisposing factors for CNS disorders. The linked polymorphic region in the 5′-promoter exists as short (s) and long (l) alleles of a 22 or 23 bp elements. The second wit...

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Detalles Bibliográficos
Autores principales: Ali, Fahad R, Vasiliou, Sylvia A, Haddley, Kate, Paredes, Ursula M, Roberts, Julian C, Miyajima, Fabio, Klenova, Elena, Bubb, Vivien J, Quinn, John P
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848977/
https://www.ncbi.nlm.nih.gov/pubmed/19860858
http://dx.doi.org/10.1111/j.1471-4159.2009.06453.x