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Identifying single-cell molecular programs by stochastic profiling

Cells within tissues can be morphologically indistinguishable yet show molecular expression patterns that are remarkably heterogeneous. Here, we describe an approach for comprehensively identifying coregulated, heterogeneously expressed genes among cells that otherwise appear identical. The techniqu...

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Detalles Bibliográficos
Autores principales: Janes, Kevin A., Wang, Chun-Chao, Holmberg, Karin J., Cabral, Kristin, Brugge, Joan S.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849806/
https://www.ncbi.nlm.nih.gov/pubmed/20228812
http://dx.doi.org/10.1038/nmeth.1442