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Identifying single-cell molecular programs by stochastic profiling
Cells within tissues can be morphologically indistinguishable yet show molecular expression patterns that are remarkably heterogeneous. Here, we describe an approach for comprehensively identifying coregulated, heterogeneously expressed genes among cells that otherwise appear identical. The techniqu...
Autores principales: | Janes, Kevin A., Wang, Chun-Chao, Holmberg, Karin J., Cabral, Kristin, Brugge, Joan S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849806/ https://www.ncbi.nlm.nih.gov/pubmed/20228812 http://dx.doi.org/10.1038/nmeth.1442 |
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