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Accumulation of intraneuronal Aβ correlates with ApoE4 genotype

In contrast to extracellular plaque and intracellular tangle pathology, the presence and relevance of intraneuronal Aβ in Alzheimer’s disease (AD) is still a matter of debate. Human brain tissue offers technical challenges such as post-mortem delay and uneven or prolonged tissue fixation that might...

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Detalles Bibliográficos
Autores principales: Christensen, Ditte Z., Schneider-Axmann, Thomas, Lucassen, Paul J., Bayer, Thomas A., Wirths, Oliver
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849938/
https://www.ncbi.nlm.nih.gov/pubmed/20217101
http://dx.doi.org/10.1007/s00401-010-0666-1