Age-associated epigenetic modifications in human DNA increase its immunogenicity

Chronic inflammation, increased reactivity to self-antigens and incidences of cancer are hallmarks of aging. However, the underlying mechanisms are not well understood. Age-associated alterations in the DNA either due to oxidative damage, defects in DNA repair or epigenetic modifications such as met...

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Detalles Bibliográficos
Autores principales: Agrawal, Anshu, Tay, Jia, Yang, Gi-Eun, Agrawal, Sudhanshu, Gupta, Sudhir
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850145/
https://www.ncbi.nlm.nih.gov/pubmed/20354270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850145/
https://www.ncbi.nlm.nih.gov/pubmed/20354270

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