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Expression of survivin detected by immunohistochemistry in the cytoplasm and in the nucleus is associated with prognosis of leiomyosarcoma and synovial sarcoma patients

BACKGROUND: Survivin, a member of the inhibitor of apoptosis-protein family suppresses apoptosis and regulates cell division. It is strongly overexpressed in the vast majority of cancers. We were interested if survivin detected by immunohistochemistry has prognostic relevance especially for patients...

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Detalles Bibliográficos
Autores principales: Taubert, Helge, Heidenreich, Chris, Holzhausen, Hans-Jürgen, Schulz, Antje, Bache, Matthias, Kappler, Matthias, Eckert, Alexander W, Würl, Peter, Melcher, Ingo, Hauptmann, Kathrin, Hauptmann, Steffen, Schaser, Klaus-Dieter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850337/
https://www.ncbi.nlm.nih.gov/pubmed/20181247
http://dx.doi.org/10.1186/1471-2407-10-65