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Solution structure of a Plasmodium falciparum AMA-1/MSP 1 chimeric protein vaccine candidate (PfCP-2.9) for malaria

BACKGROUND: The Plasmodium falciparum chimeric protein PfCP-2.9 is a promising asexual-stage malaria vaccine evaluated in clinical trials. This chimeric protein consists of two cysteine-rich domains: domain III of the apical membrane antigen 1 (AMA-1 [III]) and the C-terminal region of the merozoite...

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Detalles Bibliográficos
Autores principales: Peng, Heng, Hu, Yunfei, Zhou, Aiguo, Jin, Changwen, Pan, Weiqing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850360/
https://www.ncbi.nlm.nih.gov/pubmed/20236549
http://dx.doi.org/10.1186/1475-2875-9-76