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Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis
Autoreactive CD4(+) T lymphocytes play a vital role in the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis. Since the discovery of T helper 17 cells, there is an ongoing debate whether T helper 1, T helper 17 or both subtypes of T lymphocytes are im...
Autores principales: | Kleiter, Ingo, Song, Jian, Lukas, Dominika, Hasan, Maruf, Neumann, Bernhard, Croxford, Andrew L., Pedré, Xiomara, Hövelmeyer, Nadine, Yogev, Nir, Mildner, Alexander, Prinz, Marco, Wiese, Elena, Reifenberg, Kurt, Bittner, Stefan, Wiendl, Heinz, Steinman, Lawrence, Becker, Christoph, Bogdahn, Ulrich, Neurath, Markus F., Steinbrecher, Andreas, Waisman, Ari |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850583/ https://www.ncbi.nlm.nih.gov/pubmed/20354004 http://dx.doi.org/10.1093/brain/awq039 |
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