Targeting mTORC2 inhibits colon cancer cell proliferation in vitro and tumor formation in vivo

The mammalian target of rapamycin (mTOR), which exists in two functionally distinct complexes, mTORC1 and mTORC2 plays an important role in tumor growth. Whereas the role of mTORC1 has been well characterized in this process, little is known about the functions of mTORC2 in cancer progression. In th...

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Detalles Bibliográficos
Autores principales: Roulin, Didier, Cerantola, Yannick, Dormond-Meuwly, Anne, Demartines, Nicolas, Dormond, Olivier
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Short communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850884/
https://www.ncbi.nlm.nih.gov/pubmed/20226010
http://dx.doi.org/10.1186/1476-4598-9-57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850884/
https://www.ncbi.nlm.nih.gov/pubmed/20226010
http://dx.doi.org/10.1186/1476-4598-9-57

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