The Onconeural Antigen cdr2 Is a Novel APC/C Target that Acts in Mitosis to Regulate C-Myc Target Genes in Mammalian Tumor Cells

Cdr2 is a tumor antigen expressed in a high percentage of breast and ovarian tumors and is the target of a naturally occurring tumor immune response in patients with paraneoplastic cerebellar degeneration, but little is known of its regulation or function in cancer cells. Here we find that cdr2 is c...

Descripción completa

Detalles Bibliográficos
Autores principales: O'Donovan, Kevin J., Diedler, Jennifer, Couture, Graeme C., Fak, John J., Darnell, Robert B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850929/
https://www.ncbi.nlm.nih.gov/pubmed/20383333
http://dx.doi.org/10.1371/journal.pone.0010045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850929/
https://www.ncbi.nlm.nih.gov/pubmed/20383333
http://dx.doi.org/10.1371/journal.pone.0010045

Ejemplares similares