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The Onconeural Antigen cdr2 Is a Novel APC/C Target that Acts in Mitosis to Regulate C-Myc Target Genes in Mammalian Tumor Cells
Cdr2 is a tumor antigen expressed in a high percentage of breast and ovarian tumors and is the target of a naturally occurring tumor immune response in patients with paraneoplastic cerebellar degeneration, but little is known of its regulation or function in cancer cells. Here we find that cdr2 is c...
Autores principales: | O'Donovan, Kevin J., Diedler, Jennifer, Couture, Graeme C., Fak, John J., Darnell, Robert B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850929/ https://www.ncbi.nlm.nih.gov/pubmed/20383333 http://dx.doi.org/10.1371/journal.pone.0010045 |
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