Ganglioside GM3 Levels Are Altered in a Mouse Model of HIBM: GM3 as a Cellular Marker of the Disease

OBJECTIVE: HIBM (Hereditary Inclusion Body Myopathy) is a recessive hereditary disease characterized by adult-onset, slowly progressive muscle weakness sparing the quadriceps. It is caused by a single missense mutation of each allele of the UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kin...

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Detalles Bibliográficos
Autores principales: Paccalet, Thomas, Coulombe, Zoé, Tremblay, Jacques P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850932/
https://www.ncbi.nlm.nih.gov/pubmed/20383336
http://dx.doi.org/10.1371/journal.pone.0010055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850932/
https://www.ncbi.nlm.nih.gov/pubmed/20383336
http://dx.doi.org/10.1371/journal.pone.0010055

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