Engineering a two-helix bundle protein for folding studies

The SAP domain from the Saccharomyces cerevisiae THO1 protein contains a hydrophobic core and just two α-helices. It could provide a system for studying protein folding that bridges the gap between studies on isolated helices and those on larger protein domains. We have engineered the SAP domain for...

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Detalles Bibliográficos
Autores principales: Dodson, Charlotte A., Ferguson, Neil, Rutherford, Trevor J., Johnson, Christopher M., Fersht, Alan R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851443/
https://www.ncbi.nlm.nih.gov/pubmed/20130106
http://dx.doi.org/10.1093/protein/gzp080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851443/
https://www.ncbi.nlm.nih.gov/pubmed/20130106
http://dx.doi.org/10.1093/protein/gzp080

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