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Structure-function studies of an engineered scaffold protein derived from stefin A. I: Development of the SQM variant

Non-antibody scaffold proteins are used for a range of applications, especially the assessment of protein–protein interactions within human cells. The search for a versatile, robust and biologically neutral scaffold previously led us to design STM (stefin A triple mutant), a scaffold derived from th...

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Detalles Bibliográficos
Autores principales: Hoffmann, Toni, Stadler, Lukas Kurt Josef, Busby, Michael, Song, Qifeng, Buxton, Anthony T., Wagner, Simon D., Davis, Jason J., Ko Ferrigno, Paul
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851446/
https://www.ncbi.nlm.nih.gov/pubmed/20179045
http://dx.doi.org/10.1093/protein/gzq012