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Airway Wall Expression of OX40/OX40L and Interleukin-4 in Asthma

BACKGROUND: The costimulatory molecule OX40 and its ligand, OX40L, mediate key aspects of allergic airway inflammation in animal models of asthma, including eosinophilic airway inflammation, airway hyperresponsiveness, and T helper 2 polarization. We sought to examine OX40/OX40L and interleukin (IL)...

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Detalles Bibliográficos
Autores principales: Siddiqui, Salman, Mistry, Vijay, Doe, Camille, Stinson, Sally, Foster, Martyn, Brightling, Christopher
Formato: Texto
Lenguaje:English
Publicado: American College of Chest Physicians 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851558/
https://www.ncbi.nlm.nih.gov/pubmed/20139223
http://dx.doi.org/10.1378/chest.09-1839