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On the Conservation of the Slow Conformational Dynamics within the Amino Acid Kinase Family: NAGK the Paradigm

N-Acetyl-L-Glutamate Kinase (NAGK) is the structural paradigm for examining the catalytic mechanisms and dynamics of amino acid kinase family members. Given that the slow conformational dynamics of the NAGK (at the microseconds time scale or slower) may be rate-limiting, it is of importance to asses...

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Detalles Bibliográficos
Autores principales: Marcos, Enrique, Crehuet, Ramon, Bahar, Ivet
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851564/
https://www.ncbi.nlm.nih.gov/pubmed/20386738
http://dx.doi.org/10.1371/journal.pcbi.1000738