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S Phase Progression in Human Cells Is Dictated by the Genetic Continuity of DNA Foci
DNA synthesis must be performed with extreme precision to maintain genomic integrity. In mammalian cells, different genomic regions are replicated at defined times, perhaps to preserve epigenetic information and cell differentiation status. However, the molecular principles that define this S phase...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851568/ https://www.ncbi.nlm.nih.gov/pubmed/20386742 http://dx.doi.org/10.1371/journal.pgen.1000900 |