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Minimally perturbing a gene regulatory network to avoid a disease phenotype: the glioma network as a test case
BACKGROUND: Mathematical modeling of biological networks is an essential part of Systems Biology. Developing and using such models in order to understand gene regulatory networks is a major challenge. RESULTS: We present an algorithm that determines the smallest perturbations required for manipulati...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851584/ https://www.ncbi.nlm.nih.gov/pubmed/20184733 http://dx.doi.org/10.1186/1752-0509-4-15 |