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Calling SNPs without a reference sequence

BACKGROUND: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a reference genome sequence for the same species. These mappings can then be used to identify genetic differences among individua...

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Detalles Bibliográficos
Autores principales: Ratan, Aakrosh, Zhang, Yu, Hayes, Vanessa M, Schuster, Stephan C, Miller, Webb
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851604/
https://www.ncbi.nlm.nih.gov/pubmed/20230626
http://dx.doi.org/10.1186/1471-2105-11-130