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Physicochemical property distributions for accurate and rapid pairwise protein homology detection
BACKGROUND: The challenge of remote homology detection is that many evolutionarily related sequences have very little similarity at the amino acid level. Kernel-based discriminative methods, such as support vector machines (SVMs), that use vector representations of sequences derived from sequence pr...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851606/ https://www.ncbi.nlm.nih.gov/pubmed/20302613 http://dx.doi.org/10.1186/1471-2105-11-145 |