Emergence of Micronuclei and Their Effects on the Fate of Cells under Replication Stress

The presence of micronuclei in mammalian cells is related to several mutagenetic stresses. In order to understand how micronuclei emerge, behave in cells, and affect cell fate, we performed extensive time-lapse microscopy of HeLa H2B-GFP cells in the presence of hydroxyurea at low concentration. Mic...

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Detalles Bibliográficos
Autores principales: Utani, Koh-ichi, Kohno, Yuka, Okamoto, Atsushi, Shimizu, Noriaki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851613/
https://www.ncbi.nlm.nih.gov/pubmed/20386692
http://dx.doi.org/10.1371/journal.pone.0010089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851613/
https://www.ncbi.nlm.nih.gov/pubmed/20386692
http://dx.doi.org/10.1371/journal.pone.0010089

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