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Expression and aberrant promoter methylation of Wnt inhibitory factor-1 in human astrocytomas

BACKGROUND: Wnt inhibitory factor-1(WIF-1) acts as a Wnt-antagonists and tumor suppressor, but hypermethylation of WIF-1 gene promoter and low expression activate Wnt signaling aberrantly and induce the development of various human tumors. With this work we intended to investigate the expression and...

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Detalles Bibliográficos
Autores principales: Yang, Zhuanyi, Wang, Ying, Fang, Jiasheng, Chen, Fenghua, Liu, Jinfang, Wu, Jun, Wang, Yanjin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851677/
https://www.ncbi.nlm.nih.gov/pubmed/20334650
http://dx.doi.org/10.1186/1756-9966-29-26