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Expression and aberrant promoter methylation of Wnt inhibitory factor-1 in human astrocytomas
BACKGROUND: Wnt inhibitory factor-1(WIF-1) acts as a Wnt-antagonists and tumor suppressor, but hypermethylation of WIF-1 gene promoter and low expression activate Wnt signaling aberrantly and induce the development of various human tumors. With this work we intended to investigate the expression and...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851677/ https://www.ncbi.nlm.nih.gov/pubmed/20334650 http://dx.doi.org/10.1186/1756-9966-29-26 |