Peptide Inhibitors of Dengue-Virus Entry Target a Late-Stage Fusion Intermediate

The mechanism of membrane fusion by “class II” viral fusion proteins follows a pathway that involves large-scale domain rearrangements of the envelope glycoprotein (E) and a transition from dimers to trimers. The rearrangement is believed to proceed by an outward rotation of the E ectodomain after l...

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Detalles Bibliográficos
Autores principales: Schmidt, Aaron G., Yang, Priscilla L., Harrison, Stephen C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851732/
https://www.ncbi.nlm.nih.gov/pubmed/20386713
http://dx.doi.org/10.1371/journal.ppat.1000851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851732/
https://www.ncbi.nlm.nih.gov/pubmed/20386713
http://dx.doi.org/10.1371/journal.ppat.1000851

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