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Peptide Inhibitors of Dengue-Virus Entry Target a Late-Stage Fusion Intermediate
The mechanism of membrane fusion by “class II” viral fusion proteins follows a pathway that involves large-scale domain rearrangements of the envelope glycoprotein (E) and a transition from dimers to trimers. The rearrangement is believed to proceed by an outward rotation of the E ectodomain after l...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851732/ https://www.ncbi.nlm.nih.gov/pubmed/20386713 http://dx.doi.org/10.1371/journal.ppat.1000851 |