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Zscan4 regulates telomere elongation and genomic stability in ES cells

Exceptional genomic stability is one of the hallmarks of mouse embryonic stem (ES) cells. However, the genes contributing to this stability remain obscure. We previously identified Zscan4 as a specific marker for 2-cell embryo and ES cells. Here we show that Zscan4 is involved in telomere maintenanc...

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Detalles Bibliográficos
Autores principales: Zalzman, Michal, Falco, Geppino, Sharova, Lioudmila V., Nishiyama, Akira, Thomas, Marshall, Lee, Sung-Lim, Stagg, Carole A., Hoang, Hien G., Yang, Hsih-Te, Indig, Fred E., Wersto, Robert P., Ko, Minoru S. H.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851843/
https://www.ncbi.nlm.nih.gov/pubmed/20336070
http://dx.doi.org/10.1038/nature08882