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The HTLV-1 Tax Protein Cooperates with Phosphorylated CREB, TORC2, and p300 to Activate CRE-Dependent Cyclin D1 Transcription

Adult T-cell leukemia/lymphoma is a fatal malignancy etiologically linked to infection with the human T-cell leukemia virus (HTLV-1). The virally-encoded oncoprotein Tax activates transcription of HTLV-1 and cellular genes by cooperating with cellular transcription factors. Cyclin D1 is a pivotal re...

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Detalles Bibliográficos
Autores principales: Kim, Young-Mi, Geiger, Timothy R., Egan, Dinaida, Sharma, Neelam, Nyborg, Jennifer K.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851846/
https://www.ncbi.nlm.nih.gov/pubmed/20101207
http://dx.doi.org/10.1038/onc.2009.498