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Development and In Vitro Evaluation of Buccoadhesive Tablets of Metoprolol Tartrate
Buccoadhesive tablet of metoprolol tartrate was developed to prolong its release and improve bioavailability by avoidance of hepatic first pass metabolism during the treatment of chronic hypertension. The formulations were tested for weight, hardness, friability, content uniformity, swelling index,...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852051/ https://www.ncbi.nlm.nih.gov/pubmed/20390098 http://dx.doi.org/10.4103/0250-474X.40349 |