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Design and Optimization of Diclofenac Sodium Controlled Release Solid Dispersions by Response Surface Methodology

A 3(2) factorial design was employed to produce controlled release solid dispersions of diclofenac sodium in Eudragit RS and RL by coevaporation of their ethanol solution in a flash evaporator. The effect of critical formulation variables namely total polymer pay loads and levels of Eudragit RL on p...

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Detalles Bibliográficos
Autores principales: Shivakumar, H. N., Desai, B. G., Deshmukh, G.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852056/
https://www.ncbi.nlm.nih.gov/pubmed/20390076
http://dx.doi.org/10.4103/0250-474X.40327