Cyclin D1 repressor domain mediates proliferation and survival in prostate cancer

Regulation of the androgen receptor (AR) is critical to prostate cancer (PCa) development; therefore, AR is the first line therapeutic target for disseminated tumors. Cell cycle dependent accumulation of cyclin D1 negatively modulates the transcriptional regulation of the AR through discrete, CDK4-i...

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Detalles Bibliográficos
Autores principales: Schiewer, Matthew J., Morey, Lisa M., Burd, Craig J., Liu, Yuhong, Merry, Diane E., Ho, Shuk-Mei, Knudsen, Karen E.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852245/
https://www.ncbi.nlm.nih.gov/pubmed/19079343
http://dx.doi.org/10.1038/onc.2008.446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852245/
https://www.ncbi.nlm.nih.gov/pubmed/19079343
http://dx.doi.org/10.1038/onc.2008.446

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