Development of Azole Resistance in Aspergillus fumigatus during Azole Therapy Associated with Change in Virulence

Four sequential Aspergillus fumigatus isolates from a patient with chronic granulomatous disease (CGD) eventually failing azole-echinocandin combination therapy were investigated. The first two isolates (1 and 2) were susceptible to antifungal azoles, but increased itraconazole, voriconazole and pos...

Descripción completa

Detalles Bibliográficos
Autores principales: Arendrup, Maiken Cavling, Mavridou, Eleftheria, Mortensen, Klaus Leth, Snelders, Eveline, Frimodt-Møller, Niels, Khan, Humara, Melchers, Willem J. G., Verweij, Paul E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852403/
https://www.ncbi.nlm.nih.gov/pubmed/20404915
http://dx.doi.org/10.1371/journal.pone.0010080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852403/
https://www.ncbi.nlm.nih.gov/pubmed/20404915
http://dx.doi.org/10.1371/journal.pone.0010080

Ejemplares similares